Custom Peptides
Cayman Chemical 2MethylethcathInonhydroch 10mg
A substituted cathinone with potential for abuse; intended for research and forensic applications
Cayman Chemical Psorala corylfola nglcn 10mg
A furanocoumarin with antibacterial activities; prevents tacrine-induced cytotoxicity in HepG2 cells (EC50 = 47 μg/ml) and vascular relaxation in phenylephrine-precontracted rat aorta; weakly inhibits topoisomerase II (IC50 = 404 μM)
Cayman Chemical 15 S-Fluprostenol 10mg
An isomer of fluprostenol; a potential active metabolite to 15(S)-fluprostenol isopropyl ester
Cayman Chemical L-QuIsqualIc AcId 10mg
A natural analog of glutamate that acts as an agonist at AMPA-selective and metabotropic glutamate receptors (EC50s = 170, 10, 40, and 29 nM at GluR-A, mGluR1, mGluR3, and mGluR5, respectively), as well as (GRIK4 (Ki = 6.43 nM)
Cayman Chemical GalactosylsphngosInd18 1 10mg
A bioactive sphingolipid; potentiates LPS-induced production of inflammatory cytokines, decreases the mitochondrial membrane potential, and induces cell death in mouse astrocytes; induces demyelination of mouse cerebellar slices at 0.1 and 1 µM; inhibits PDGF-induced translocation of PKC to the cell surface and induces apoptosis in MO3.13 oligodendrocytes; inhibits PPARα-mediated gene transcription in C6 glial cells at 10 and 15 µM; levels are increased in postmortem brain from patients with Krabbe disease
Cayman Chemical BalsalazIde 10mg
A prodrug form of 5-ASA; cleaved by bacterial azoreductases in the intestinal lumen to release 5-ASA; decreases IL-2 levels and increases IL-6 levels in the serum and colonic mucosa membrane, as well as decreases micro- and macroscopic colonic damage, in a rat model of DNCB-induced colitis at 600 mg/kg per day
Cayman Chemical Swansonn 10mg
An indolizidine alkaloid naturally found in certain plants that inhibits N-linked glycoside hydrolases, preventing the processing of asparagine-linked glycoproteins; reversibly inhibits lysosomal α-mannosidase and Golgi α-mannosidase II (IC50 = 0.2 μM); shown to have antiproliferative and antimetastatic effects on cancer cells in culture and in mice
Cayman Chemical 13Z 16ZDocosadIenoIc AcId 10mg
A natural ω-6 PUFA; an agonist of FFAR4 (GPR120) that strongly inhibits the secretion of ghrelin by isolated mouse gastric cells
Cayman Chemical AHU377calcIum salt 10mg
A prodrug form of LBQ657; increases plasma levels of ANF in concious rats and anesthetized dogs at 10 and 30 mg/kg, respectively; increases ANF-induced urinary sodium excretion in anesthetized rats at 30 mg/kg
Cayman Chemical trnsOcImen 10mg
A monoterpene; a volatile compound involved in plant-plant signaling and plant defense against pests; emission from L. japonicus plants is induced within 24 hours of spider mite (T. urticae) infestation; conditioning of tomato plants using VOCs from transgenic tobacco plants overexpressing trans-β-ocimene synthase increases production of VOCs, reduces the number of aphids (M. euphorbiae) that settle on the plant and the number of nymphs produced by the aphids that settle, as well as increases the number of landings of the aphid parasitoid A. ervi
ABclonal Technology Phospho-IRAK4-Thr345/Ser346 Rabbit pAb
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Cayman Chemical ParaxnthIn 10mg
An active metabolite of caffeine; an adenosine A1 and A2 receptor antagonist (Kis = 35 and 22 µM, respectively); increases striatal cGMP and extracellular striatal dopamine levels and locomotor activity, as well as inhibits motor depression induced by CPA or CGS 21680 in rats not habituated to caffeine at 30 mg/kg; promotes wakefulness and increases locomotor activity and core temperature in narcoleptic transgenic mice without increasing behavioral anxiety
Cayman Chemical 14-nhydrodIgItoxIgenIn 10mg
A cardenolide; reduces the activity of guinea pig heart Na+/K+-ATPase by 15% at 10 µM
Cayman Chemical SNBocLHomoserIn ethyl 10mg
A synthetic intermediate in the synthesis of unsaturated caprolactams and monomer units for oxy-peptide nucleic acids from the starting material L-homoserine
Cayman Chemical VulpInIc AcId 10mg
A lichen metabolite with diverse biological activities; active against various bacteria (MICs = 4-16 μg/ml); prevents UVB-induced apoptosis, cytotoxicity, and cytoskeletal modifications in HaCaT human keratinocytes from 25-800 μM; increases scratch wound healing of HaCaT cells; reduces hydrogen peroxide-induced production of ROS and cytotoxicity in HUVECs at 15 μM